RI 2024/122. Safety, Health and Welfare at Work (Carcinogens, Mutagens and Reprotoxic Substances) Regulations 2024. Regulation published 29th March. These Regulations revoke the Safety, Health and Welfare at Work (Carcinogens) Regulations, 2001 (RI 2001/78). These Regulations give effect to Directive (EU) 2022/431 on the protection of workers from the risks related to exposure to carcinogens or mutagens at work.