HSE have published guidance to companies which supply or purchase substances, mixtures or articles to and from the EU/EEA and the UK in the case of a “no-deal” Brexit occurring. They state that in a “no-deal” scenario, the UK and the EU regulatory agencies would operate independently from each other. They add that in order to maintain or gain access to both markets, companies will need to ensure that the substances, or substances within a mixture or article, are registered separately with both agencies (ECHA and the UK Agency, i.e. the HSE). http://www.hse.gov.uk/brexit/reach.htm